Previous Members

Previous Researchers & Post-docs

Fulai Wang

Zhaohui Xu

Hengho Wong

Nagendra Thakur

specific information

Yu Kyung Lee

Seong Sook Heo

Hye Won Jeong

Sang Hyun Park

Sung Jae Yang

Hyun Sook Lee

Jiang Hao

Kyung Hwa Ryu

Chen Shi

Kyung Hee Gang

Ki Jun Jeong

Details

1. Research Interest

2. Education

3. Experience and Academic/Research Activity

4. Publications


5. Invited Lectures

6. International Conferences

7. Domestic Conferences

Sung Jin Kim

Details

Professional Experience

 

2009.3 - present   Postdoctorial Fellow, Institute for Systems Biology at Seattle

2009.1 - 2009.3 Senior Research Scientist, Industrial Biotechnology and Bioenergy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 111 Gwahangno, Yuseong-gu, Daejeon 305-806, Republic of Korea

2008  - present     Editorial Advisory Board Member, Recent Patents on Biotechnology, Bentham Science Publishers, USA

2006.9 - 2009.2     Lecturer, Functional Genomics Major, University of Science and Technology (UST), Daejeon, Korea

2004.7 - 2008.12   Senior Research Scientist, Systems Microbiology Research Center, KRIBB2003.7 - 2004.6     Senior Research Scientist, Genome Research Center, KRIBB

2003   - 2006         Committee Member, Korean Society for Bioinformatics (KSBI)

2002.11 - 2003.6    Post. Doc National Center for Genome Informatics, KRIBB

1998. 3 - 2002. 2    Teaching Assistant, Department of Chemical Engineering, Korea Advanced Institute of Science and Technology (KAIST)

 

ad hoc Reviewer

 

Biotechnology and Bioengineering / Biotechnology Journal / Process Biochemistry

BMC Genomics / BMC Bioinformatics / Computer Methods and Programs in Biomedicine / Gene

 

Educational Background

 

1998.3 - 2002.8   Department of Chemical & Biomolecular Engineering, KAIST (Ph.D.)

(Dissertation: Development of Escherichia coli DNA microarray and global gene expression profiling in Escherichia coli. Supervor: Sang Yup Lee)

1996.3 - 1998.2   Department of Chemical Engineering, KAIST (M. S.)

                        (Dissertation: Development of fermentation strategies for the production of poly (γ-lutamic acid) and insulin-like growth factor I. Supervisor: Sang Yup Lee)

1992.3 - 1996.2   Department of Chemical Engineering, KAIST (B. S.)

 

Research Interests

 

Metabolic Engineering / Synthetic Biology

Pathogenomics / Host-Pathogen Interactio

Bioinformatics / Omics Analysis

Systems Microbiology

 

ad hoc Awards

 

Award for Excellent Staff, KRIBB (2007.2.1)

Award for Most Excellent Poster, Korean Society for Biotechnology and Bioengineering (2002.4.13)

 

Media Recognition

 

2007. 2. 6.          Daejonilbo (newspaper), "Scientist opening 21 century - Dr. Sung Ho Yoon"

2006.11.28.        MBC TV newstoday, "Development of pathogenicity island database"

2006.11.28.         YTN TV "Development of pathogenicity island database"

 

Publications

 

20) Yoon SH, Kim SK, and Kim JF "Secretory production of recombinant proteins in Escherichia coli" Recent Patents on Biotechnology (2010) (in press)

 

19) Barrick JE, Yu D-S, Yoon SH, Jeong H, Oh TK, Schneider D, Lenski RE, and Kim JF "Genome dynamics in a long-term experiment with Escherichia coli" Nature 461:1243-1247 (2009)

 

18) Jeong H, Barbe V, Lee CH, Vallenet D, Yu D-S, Choi S-H, Couloux A, Lee S-W, Yoon SH, Cattolico L, Hur C-G, Park H-S, Ségurens B, Kim SC, Oh TK, Lenski RE, Studier FW, Daegelen P, and Kim JF "Genome sequences of Escherichia coli B strains REL606 and BL21(DE3)" J. Mol. Biol. (Published online 26 September 2009)

 

17) Yoon SH, Jeong H, Kwon S-K, and Kim JF "Chapter 1. Genomics, biological features, and biotechnological applications of Escherichia coli B: "Is B for better?!"", pp. 1-17, In: Systems Biology and Biotechnology of E. coli, Lee SY (ed.) Springer, Berlin, Germany (2009. 4)

 

16) Kim JF, Jeong H, Yu DS, Choi S-H, Hur C-G, Park M-S, Yoon SH, Kim D-W, Ji GE, Park H-S, and Oh TK "Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp. lactis AD011" J. Bacteriol. 191:678-679 (2009)

 

15) Jeong H, Yoon SH, Yu D-S, Oh TK, and Kim JF "Recent progress in microbial genome projects of Korea" Biotechnol. J. 3:601-611 (2008)

 

14) Nam D, Yoon SH, and Kim JF "Ensemble learning of genetic networks from time-series expression data" Bioinformatics 23:3225-3231 (2007)

 

13) Yoon SH, Park YK, Lee S, Choi D, Oh TK, Hur C-G, and Kim JF "Towards pathogenomics: a web-based resource for pathogenicity islands" Nucleic Acids Res. 35:D395-D400 (2007)

 

12) Hur C-G, Kim S, Kim CH, Yoon SH, In YH, Kim C, and Cho HG "FASIM: Fragments assembly simulation using biased-sampling model and assembly simulation for microbial genome shotgun sequencing" J. Microbiol.Biotechnol. 16:683-688 (2006)

 

11) Jiang H, Shang L, Yoon SH, Lee SY, and Yu Z "Optimal production of poly-¥￧lutamic acid by metabolically engineered Escherichia coli" Biotechnol. Lett. 28:1241-1246 (2006)

 

10) Jeong H, Yoon SH, Lee HK, Oh TK, and Kim JF "Lessons from the sea: genome sequence of an algicidal marine bacterium Hahella chejuensis (적조 살상 해양 미생물 Hahella chejuensis의 유전체 구조)" Kor. J. Microbiol. Biotechnol. 34:1-6 (2006)

 

9) Jeong H, Yim JH, Lee C, Choi SH, Park YK, Yoon SH, Hur CG, Kang HY, Kim D, Lee HH, Park KH, Park SH, Park HS, Lee HK, Oh TK, and Kim JF "Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent", Nucleic Acids Res. 33:7066-7073 (2005)

 

8) Yoon SH, Hur C-G, Kang HY, Kim YH, Oh TK, and Kim JF "A computational approach for identifying pathogenicity islands in prokaryotic genomes" BMC Bioinformatics 6:184 (2005)

 

7) Yoon SH, Han MJ, Lee SY, Jeong KJ, and Yoo JS "Combined transcriptome and proteome analysis of Escherichia coli during the high cell density culture", Biotechnol. Bioeng. 81:753-767 (2003)

 

6) Kim JS, Yoon SH, and Lee SY "Development of database systems by integrating heterogeneous metabolic databases", Genome Informatics 13:486-487 (2002)

 

5) Heo WJ, Yoon SH, and Lee SY "Global gene expression profiling of E. coli and its mutant unable to produce acetate", Genome Informatics 13: 270-271 (2002)

 

4) Yoon SH and Lee SY "Comparison of transcript levels by DNA microarray and metabolic flux based on flux analysis for the production of poly-γ-glutamic acid in recombinant Escherichia coli", Genome Informatics 13:587-588 (2002)

 

3) Chung BH, Choi YJ, Yoon SH, Lee SY, and Lee YI "Process development for production of recombinant human insulin-like growth factor-I in Escherichia coli", J. Ind. Microbiol. Biotechnol. 24:94-99 (2000)

 

2) Yoon SH, Do JH, Lee SY, and Chang HN "Production of poly-γ-glutamic acid by fed-batch culture of Bacillus licheniformis" Biotechnol. Lett. 22:585-588 (2000)

 

1) Yoon SH, Choi J, and Lee SY "Development of DNA chip microarrayer" J. Microbiol.Biotechnol., 10:21-26 (2000) (The result was presented at Nature Genetics, Microarray Meeting (1999)

 

Patents

 

3) Jeong H, Han JH, Yoon SH, Ryu C-M, Kim JF, Oh TK, Jung MH, Yoon SP "Method for Selecting Alcohol Resistant Variants of Microorganism Using Mutagenesis by Proton Beam Irradiation" Korean Patent: appl. 10-2009-0080393 (2009.08.28)

정해영 한지희 윤성호 류충민 김지현 오태광 정명환 윤상필 “양성자 빔 조사에 의한 돌연변이 유도방법을 이용한 알코올 내성 미생물 변이체의 선별 방법” 특허출원번호10-2009-0080393 (2009.08.28)

2) Hong JW, Kim JF, Oh TK, and Yoon SH "A fluidic array system for biological, chemical, and biochemical assessments" PCT/US08/59777 (PCT/US08/59777) (filed on April 9, 2008)

 

1) Lee SY and Yoon SH "Methods for producing high concentration of poly (gamma-glutamic acid) by fed-batch culture of Bacillus licheniformis" Korean Patent: appl. 97-67605 (12. 10. 1997), registered 250627 (1. 5. 2000)

이상엽, 윤성호 "바실러스 리케니포니스에 의한 폴리글루탐산(g-PGA)의 고효율 생산방법" 특허출원번호 10-1997-0067605 (1997. 12. 10.), 등록번호 1002506270000 (2000. 01. 05)

 

Program Registration

 

2) 김지현, 윤성호, 허철구, 오태광. "미생물 유전체 내에서 외래에서 유입된 병원성 유전자군인 pathogenicity island를 예측하는 방법" (등록일자: 2007년 7월 29일; 등록번호: 2007-01-129-3962)

 

1) 김지현, 윤성호, 허철구, 박영규, 오태광. "미생물 유전체 내에서 외래에서 유입된 병원성 유전자군인 pathogenicity island를 분석, 예측하는 시스템" (등록일자: 2007년 7월 29일; 등록번호: 2007-01-129-3964)

 

Essays

 

6) Yoon SH "Systems and Synthetic Biology" In State of the Art Report on Microbial Genomics 미생물유전체 연구동향 분석연구), Ministry of Science and Technology, Korea (2007)

 

5)Yoon SH “최신 기술동향: Biolog사의 Phenotype Microarray (PM) Technology” 미생물과 산업, 32(2): 28-29, 한국미생물학회 (2006)6)

 

4) 이승구, 김지현, 정흥채, 송재준, 류충민, 윤성호 “Development of Platform Technologies for Synthetic Biology” (바이오기반 경제구축을 위한 합성생물학 핵심기술 개발), KRIBB, Korea (2006)

 

3) 김지현, 정해영, 윤성호, 박승환 “시스템 미생물학 : 유전체 해독에서 네트워크 재설계까지”, e-생물산업, 16(3) (2003)

 

2) Kim JS, Yoon SH, and Lee SY "미생물 게놈 연구", BioZine (http://biozine.kribb.re.kr) (2001.6)

 

1) Lee SY, Yoon SH, Im GB, and Cho YK "GenomicsDNA chip" News & Information for Chemical Engineers, 18(3): 307-311 (2000)

 

Invited talks

 

14) "Computational identification of pathogenicity islands in prokaryotic genomes" KOGO 2009 Winter Symposium, YongPyung Resort, Gangwon-do, Korea (2009.01.15)

13)  "Multi-omics-based Systems Approach Captures the Whole-cellular Features of closely related Escherichia coli B and K-12" International Symposium on Microbiology, Daejeon convention center, Daejeon, Korea (2008. 5.16)

12)  "Integrated Omics Analysis of Escherichia coli B and K-12" International Meeting of the Federation of Korean Microbiological Societies, Seoul KyoYuk MunHwa HoeKwan, Seoul, Korea ( 2007.10.12)

11)  "In silico identification of pathogenicity islands in pathogenic genomes", BIO KOREA 2007, COEX, Seoul , Korea (2007. 9.13)

10)  "General Concepts of Systems Biology", National Institute for Mathematical Sciences (NIMS), Daejeon, Korea (2007. 7.13)

9)      "PAIDB: a web-based resource for pathogenicity islands", 신변종 전염병 출현 조기탐지 기반사업 Workshop, Korea Centers for Disease Control and Prevention, Seoul, Korea (2007. 6.22)

8)      "Systems Microbiology" Korea Institute of Oriental Medicine, Daejeon , Korea (2007. 5.1)

7)   "Computational approach for identifying genomic and pathogenicity islands in prokaryotic genomes", National Institute for Mathematical Sciences (NIMS), Daejeon, Korea (2007. 2.28)

6)      "Microarray Experiment and Image Analysis", The Korean Society for Microbiology and Biotechnology. BEXCO Convention Hall, Pusan, Korea (2006. 6. 18)

5)      "Systems Microbiology" Korea Maritime University, Division of Civil and Environmental Engineering (Major of Environmental Engineering), Pusan, Korea (2006. 5. 4)

4)      "Genome chip analysis workshop" KRIBB Conference - Synthetic and Systems Biology of Escherichia coli, KRIBB, Daejeon, Korea (2006. 4.27)

3)   "A Computational Approach for Identifying PathogenicityIslands in Prokaryotic Genomes", The Korean Society for Microbiology and Biotechnology. Korea University, Seoul , Korea (2005. 7. 1)

2)      "Genomic Islands & Pathogenicity Islands", International Meeting of the Federation of Korean Microbiological Societies, Seoul , Korea (2005.10.21)

1)      "Applications of DNA microarray: transcriptome profiling", The 1st  International Symposium on Environmental Biosensors and DNA Microarrays for Environmental Biomonitoring, Kwangju Institute of Science and Technology, Korea (2002.5.20)

Jeong Hwa Lim

Details

Education


Soon Ho Hong



Details

1. Research Interest

2. Education

3. Award

4. Research Activity


Sang Jun Lee

Details

1. Research Interest

2. Education

3. Industrial  & Academic Experiences

4. Publications

           Lee, S.J. (2001) "Genetic studies for the overproduction of protein in Bacillus sp.", Bioindustry News 14(3) 9-12

5. Patents

6. International Presentation 

7. Invited Speaker

8. Professional Membership

9. Fellowship

Yoon Jeong Lee

Details

 Education

Bo Kyeng Hou

Details

 1. Research Interest

2. Education

3. Research Experiences

4. Awards

5. Software

 6. Publications

1. Lynda B.M. Ellis, Bo Kyeng Hou, Wenjun Kang, and Lawrence P. Wackett , "The University of Minnesota Biocatalysis/Biodegradation Database: Post-Genomic Data Mining", Nucleic Acids Research, 31, 262-265 (2003).

 2. Bo Kyeng Hou, Lawrence P. Wackett, and Lynda B.M. Ellis, "Microbial Pathway Prediction: A Functional Group Approach", Journal of Chemical Information and Computer Sciences, 43:1051-1057 (2003).

3. Bo Kyeng Hou, Lynda B.M. Ellis, and Lawrence P. Wackett , "Encoding Microbial Metabolic Logic: Predicting Biodegradation". Journal of Industrial Microbiology & Biotechnology, submitted (2003).

1.  D.M. An, B.K. Hou, K.S. Hwang, "Automatic Synthesis of Operating Procedures for Safe Emergency Operation", HWAHAK KONGHAK, 39(1), 30-35 (2001).

2.  B.K. Hou, K.S. Hwang, "Integrated Framework for Operating Procedure Synthesis Based on Constraint Propagation", HWAHAK KONGHAK, 39(3), 285-291 (2001).

3.  B.K. Hou, K.S. Hwang, "Operating Procedure Synthesis of Chemical Plants using Partial Order Algorithm", HWAHAK KONGHAK, 39(3), 300-306 (2001).

4.  B.K. Hou, K.S. Hwang, "Knowledge Framework and Algorithm for Automating HAZOP Analysis of Batch Processes", HWAHAK KONGHAK, 39(3), 292-299 (2001).

5.  B.K. Hou, K.S. Hwang, "Development of Automatic Synthesis System for Operating Procedures Using Temporal Logic and Description Logic", KIGAS, 5(1) 37-44 (2001).

6.  B.K. Hou, K.S. Hwang, "Development of Operator Training System Using Multimedia", KIGAS, 5(1), 25-30 (2001).

7.  B.K. Hou, K.S. Hwang, "Automatic Synthesis of Fault Tree Using Object-oriented Unit Modeling", KIGAS 5 (1), 21-28 (2001).

8.  Y.Y. Ok, B.K. Hou, K.S. Hwang, "Deviation-propagation models for automating HAZOP analysis of batch processes", KIGAS, 3(2), 35-42 (1999).

9.  J.M. Lee, B.K. Hou, K.S. Hwang, "Object-Oriented modeling for automated HAZOP analysis", Journal of KIIS, 13(1), 77-84 (1998).

10.  H.K. Lee, B.K. Hou, K.S. Hwang, "A Modeling for Automated Fault Tree Synthesis of Chemical Processes", KIGAS, 2(3), 12-17 (1998).

11.  B.K. Hou, D.M. An, K.S. Hwang, "An expert system for preventing hazardous conditions in boiler plants", HWAHAK KONGHAK, 34(6), 750-756 (1996).

1.  S.I. Lee, B.K. Hou, K.S. Hwang, "Metameric color matching of paint with neural network", Theories and Applications of Chem. Eng, 5(2), 2509-2512 (1999).

2.  B.K. Hou, K.S. Hwang, "An integrated framework for operating procedure synthesis of chemical plants", Theories and Applications of Chem. Eng, 4(1), 517-520 (1998).

3.  B.K. Hou, D.M. An, K.S. Hwang, "A modelling of recipe-based procedural controllers in batch processes", Theories and Applications of Chem. Eng, 3(1), 201-204 (1997).

4.  B.K. Hou, D.M. An, K.S. Hwang, "A modeling for hybrid intelligent systems of batch processes using petri net", Theories and Applications of Chem. Eng, 2(2), 1431-1434 (1996).

5.  M.Y. Noh, B.K. Hou, K.S. Hwang, "A knowledge-based expert system for automating HAZOP analysis considering discontinuity", Theories and Applications of Chem. Eng, 5 (2), 2645-2648 (1999).

1.  K.S. Hwang, B.K. Hou, D. Shin, E.S. Yoon, "Development of a Temporal Logic for the Automated Operating Procedure Synthesis in Chemical Plants", The 8th APCChE Congress, 2137-2140, Seoul, 1999.

2.  Lynda B. M. Ellis, Larry P. Wackett, Wenjun Kang, Bo Kyeng Hou, and Tony Dodge, "Microbial Metal and Metalloid Metabolism and Beyond" Research abstracts from the DOE Genome Program Contractor-Grantee Workshop, held January 27-31, 2002, in Oakland, CA

3.  Bo Kyeng Hou, Wenjun Kang, Larry P. Wackett and Lynda B.M. Ellis, "219A. Predicting Microbial Metabolism: A Functional Group Approach." ISMB 2002 in Edmonton, August 3-7.

4.  Lynda B. M. Ellis, Bo Kyeng Hou, Larry P. Wackett, "Encoding metabolic logic: Predicting biodegradation." submitted to Division of Computers in Chemistry for the 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004.

Ji Hye Yoon

Details

 Education

Jong Pil Park

Details

 1. Education

2. Research Interest

3. Additional Experience

4. Awards

5. Publications and book chapter

  1)Papers:

1. Park, J.P., Kim, D.H., Kim, D.S., and Yun, J.W.: Enzymatic production of inulo-oligosaccharides from chicory juice. Biotechnol Lett, 20(4) 385~388 (1998)

2. Park JP, Bae JT, and Yun JW : Critical effect of ammonium ions on the enzymatic reaction of a novel transfructosylating enzyme for fructooligosaccharide formation from sucrose. Biotechnol Lett, 21(10) (1999) 

3. Park JP, Bae JT, You DJ, Kim BW and Yun JW: Production of inulooligosaccharides from inulin by a novel endoinulinase from Xanthomonas sp. Biotechnol Lett, 21(12) (1999)

4. Yun JW, Park JP, Song CH, Lee CY, Kim JH, and Song SK : Continuous production of inulo-oligosaccharides from chicory juice by immobilized endoinulinase. Bioprocess Eng, 22(3) 189~194 (2000)

5. Kim BW, Kwon HJ, Park YH, Nam SW, Park JP and Yun JW : Production of a novel transfructosylating enzyme from Bacillus macerans EG-6. Bioprocess Eng, 23(1) 11~16 (2000)

6. JT Bae, J Sinha, JP Park, CH Song, and JW Yun : Optimization of submerged culture conditions for exo-biopolymer production by Paecilomyces japonica. J Microbiol Biotechnol, 10 (4) 482~487 (2000)

7. Kim YM, Park JP, Sinha J, Lim KH, Yun JW : Acceptor reaction of a novel transfructosylating enzyme from Bacillus sp.. Biotechnol Lett, 23(1) 13~16 (2001)

8. Cho YJ, Sinha J, Park JP, Yun JW : Production of inulooligosaccharides from chicory extract by endoinulinase from Xanthomonas oryzae No.5. Enzyme Microb Technol, 28(4-5), 439~445 (2001)

9. JT Bae, JP Park, J Sinha, CH Song and JW Yun: Effect of carbon source on the mycelial growth and exo-biopolymer production by submerged culture of Paecilomyces japonica. J Biosci Bioeng, 91(5) 522~524 (2001)

10. Park JP, Yun JW : Utilization of chicory roots for microbial endoinulinase production. Lett Appl Microbiol, 33(3) 183~187 (2001) 

11. JP Park, TG Oh, JW Yun : Purification and characterization of a novel fructosyltransferase by Bacillus macerans EG-6. Process Biochem, 37, 471~476 (2001) 

12. Park JP, SW Kim, HJ Hwang and JW Yun :Optimization of submerged culture conditions for the mycelial growth and exo-biopolymer production by Cordyceps millitaris. Lett Appl Microbiol, 32, 1~6 (2001)

13. J. Sinha, JT Bae, JP Park, KH Kim, CH Song, and JW Yun: Changes in morphology of Paecilomyces japonica and its effect on broth rheology during production of exo-biopolymer. Appl Microbiol Biotechnol, 56, 88~92 (2001)

14. YJ Cho, J. Sinha, JP Park, JW Yun: Production of inulooligosaccharides from a dual endoinulinase system of Xanthomonas sp. and Pseudomonas sp. Enzyme Microb Technol, 29, 428~433 (2001)

15. J Sinha, JT Bae, JP Park, JW Yun: Effect of substrate concentration on broth rheology and fungal morphology during exo-biopolymer production by Paecilomyces japonica in a bioreactor. Enzyme Microb Technol, 29, 392~399 (2001)

16. JP Park, CH Song, JW Yun : Stimulatory effect of plant oils and fatty acids on the exo-biopolymer production in Cordyceps militaris. Enzyme Microb Technol. 31, 250-255 (2002)

17. JP Park, YM Kim, SW Kim, HJ Hwang, YJ Cho, YS Lee, CH Song, JW Yun : Effect of agitation intensity on the exo-biopolymer production and mycelial morphology in Cordyceps militaris. Lett Appl Microbiol. 34(6), 433~438 (2002)

18. YJ Cho, JP Park, HJ Hwang, SW Kim, JW Choi, JW Yun: Production of red pigment by submerged culture of Paecilomyces sinclairii. Lett Appl Microbiol. 35(3) , 195-202 (2002) 

19. SW Kim, HJ Hwang, JP Park, YJ Cho, CH Song,, JW Yun : Mycelial growth and exo-biopolymer production by submerged culture of various edible mushrooms under different media. Lett Appl Microbiol. 34(1) 56~61 (2002)

20. JP Park, YM Kim, SW Kim, HJ Hwang, YJ Cho, YS Lee, CH Song, JW Yun : Effect of aeration rate on the mycelial morphology and exo-biopolymer production in Cordyceps militaris. Process Biochem. 37, 1257~1262 (2002).

21. Park SJ, Park JP, Lee SY : Production of poly(3-hydroxybutyrate) from whey by fed-batch culture of recombinant Escherichia coli in a pilot-scale fermentor. Biotechnol Lett 24(3), 185-189 (2002)

22. Park, S.J, Park, J.P, Lee, S.Y. " Metabolic engineering of Escherichia coli for the production of medium -chain-length polyhydroxyalkaroates rich in specific monomers", FEMS Microbiol. Lett. 214:217-222 (2002)

23. Park, S.J., Park, J.P., Lee, S.Y., and Doi, Y., "Enrichment of specific monomer in medium-chain-length poly (3-hydroxyalkanoates) by amplification of fadD and fadE genes in recombinant Escherichia coli ", Enzyme Microbial Technol., 33 : 62-70 (2003)

24. Hong SH, Park S J, Moon S Y, Park J P and Lee SY . In Silico prediction of the importance of Enter-Doudoroff pathway in poly(3-hydroxybutyrate) production. Biotechnol Bioeng. 83(7) : 854-863 (2003)

25. Jong Pil Park, Seok Jae Lee, Tae Jung Park, Kyung-Bok Lee, Insung S. Choi, Sang Yup Lee, Min-Gon Kim and Bong Hyun Chung. Microcontact printing of biotin for selective immobilization of streptavidin-fused proteins and SPR analysis. BBE 9:137-142 (2004)

26. Park, T.J., Lee, K.-B., Lee, S.J., Park, J.P., Lee, Z.-W., Lee, S.Y., and Choi, I.S. "Micropatterns of spores displaying heterologous proteins", J. Am. Chem. Soc., 126(34):10512-10513 (2004).

27. Jong Pil Park, Seok Jae Lee, Tae Jung Park, Kyung-Bok Lee, Insung S. Choi, Min Gon Kim, Bong Hyun Chung, Zee-Won Lee, and Sang Yup Lee: Micropatterning proteins on polyhydroxyalkanoate substrates by using the substrate binding domain as a fusion partner. Biotechnol. Bioeng, In Press (2005)

28. S.J. Lee, J.P. Park, T. J. Park. S.N. Lee, J.K. Park, S.Y. Lee. Visual detection of specific protein-protein interaction via PHB microsphere using substrate binding domain. in preparation , Anal. Chem, being revised (2005)

  2) Book chapter:

1. Lee, S.Y., Park, S.J., Park, J.P., Lee, Y. and Lee, S.H. "Economic aspects of biopolymer production", Biopolymers Vol.10, Ch.10, pp.307-337, VCH-Wiley, Weinheim Germany (2003)

2. Polyhydroxyalkanoates in nanobiotechnology: application to protein-protein interaction studies, Horizon Scientific Prss, Submitted (2005).

  3) Patents:

7

6. Presentation

  1) Domestic Conference

1. JP Park, DH Kim and JW Yun : Inulo-oligosaccharide production using chicory juice from Pseudomonas sp. Annual Meeting of the Korean Society for Biotechnology and Bioengineering, (1998.4)

2. JP Park, JW Yun : Enzymatic production of inulo-oligosaccharide from chicory juice by endoinulinase immobilized on carrier materials. Annual Meeting of the Korean Society for Biotechnology and Bioengineering, (1998.10)

3. JH Kim, JP Park, JW Yun and SK Song : Continuous production of inulooligosaccharides from chicory juice by immobilized endoinulinase. Annual Meeting of the Korean Society for Biotechnology and Bioengineering,(1999.4)

4. JP Park, BC Oh, TK Oh and JW Yun : Purification and characterization of a novel transfructosylating enzyme from Bacillus sp. Annual Meeting of the Korean Society for Applied Microbiology, (1999.4)

5. JP Park, JW Yun : Production of inulooligosaccharides from inulin by Xanthomonas sp." Annual Meeting of the Korean Society for Applied Microbiology, (1999. 10).

6. JP Park, JT Bae, JW Yun : Critical effects of ammonium ions on the enzymatic reaction of a novel transfructosylating enzyme for fructooligosaccharide production from sucrose. Annual Meeting of the Korean Society for Applied Microbiology (1999.10)

7. JT Bae, J Sinha, JP Park and JW Yun : Optimization of culture conditions for exo-biopolymer production by Paecilomyces japonica. Annual Meeting of the Korean Society for Biotechnology and Bioengineering (2000.4)

8. JP Park, J Sinha and JW Yun : Utilization of chicory roots as a carbon source for endoinulinase production in Xanthomonas sp. Annual Meeting of the Korean Society for Applied Microbiology, (2000.4)

9. JP Park, JT Bae and JW Yun : Inulo-oligosaccharide production using chicory juice from Xanthomonas sp. Annual Meeting of the Korean Society for Applied Microbiology, (2000.4)

10. YJ Cho, JP Park, J Sinha and JW Yun : Inulo-oligosaccharide production using chicory juice from Xanthomonas sp. Annual Meeting of the Korean Society of Food Science and Technology (2000.5)

11. JT Bae, J Sinha, JP Park, CH Song and JW Yun : Application of rotating simplex method for optimization of the physical parameters for exo-biololymer production by Paecilomyces japonica in batch bioreactor. Annual Meeting of the Korean Society for Applied Microbiology, (2000. 10)

12. JP Park, J Sinha, CH Song and JW Yun : Optimization of submerged culture conditions for the mycelial growth and exo-biopolymer production by Cordyceps millitaris. Annual Meeting of the Korean Society for Applied Microbiology (2000.11)

13. YM Kim, JP Park and JW Yun : Acceptor reactions of a novel transfructosylating enzyme from Bacillus sp. Annual Meeting of the Korean Society for Biotechnology and Bioengineering (2000.11)

14. YJ Cho, JP Park, J Sinha and JW Yun : Production of inulooligosaccharides from inulin by a dual endoinulinase system. Annual Meeting of the Korean Society for Biotechnology and Bioengineering (2000.11)

15. YJ Cho, JP Park, JW Yun: Production of the water-soluble red pigment from mycelial culture of Paecilomyces sinclairii. Annual Meeting of the Korean Society for Applied Microbiology, (2001. 6.20-22)

16. YM Kim, JP Park, JW Yun: Optimization of submerged culture conditions for the mycelial growth and exo-biopolymer production. Annual Meeting of the Korean Society for Applied Microbiology, (2001.6.20-22)

17. HJ Hwang, SW Kim, JP Park, JW Yun: A comparative study of effects of synthetic medium for mycelial growth and exo-biopolymer production by edible mushrooms. Annual Meeting of the Korean Society for Applied Microbiology, (2001.6.20-22)

18. SW Kim, HJ Hwang, JP Park, JW Yun: Production of exo-biopolymers by submerged culture of various insect-born fungi. Annual Meeting of the Korean Society for Applied Microbiology, (2001.6.20-22)

19. Park, J.P., Park, S.J. and Lee, S.Y. : Production and characterization of ultra-high-molecular weight poly(3-hydroxybutyrate) by recombinant Escherichia coli, Annual meeting of Korean society for Biotechnology and Bioengineering Symposium, Seoul, November(2001)

20. Park, S.J., Park, J.P. and Lee, S.Y. : Biosynthesis of medium-chain-length poly(3-hydroxyalkanoates) by metabolically engineered Escherichia coli strains, Annual meeting of Korean society for Biotechnology and Bioengineering Symposium, Seoul, November(2001)

21. Park, S.J., Park, J.P. and Lee, S.Y. : Production of poly(3-hydroxybutyrate) by recombinant Escherichia coli strain in pilot-scale fermentor from whey, KIChE meeting, Taejon , Korea (2001)

22. Park,.J.P., Park, S.J., and Lee, S.Y. : Characterization of (R)-specific enoyl-CoA hydratase genes from Pseudomonas sp. MBEL21 and their use for polyhydroxyalkanoate synthesis, Annual meeting of Korean Society for Biotechnology and Bioengineering Symposium, Chungju , October 10-12(2002)

23. Park.S.J, Park,J.P., and Lee, S.Y. : Evaluation of the roles of 3-ketoacyl-ACP reductases in the polyhydroxyalkanoates in recombinant Escherichia coli, Annual meeting of Korean society for Biotechnology and Bioengineering Symposium, Chungju , October 10-12(2002)

24. Park, J.P., Park, S.J., and Lee S.Y. : Production of medium-chain-length polyhydroxyalkanoates by a newly isolated strain of Pseudomonas sp. MBEL21, KMB Meeting, Gyunbook Univ., October,26(2002)

25. Park,J.P., Park, S.J., and Lee, S.Y. : Medium-chain-length polyhydroxyalkanoate biosynthesis and accumulation in metabolic engineered recombinant E.coli, KMB meeting,Gyunbook univ., October,26(2002)

26. Hong SH, Park S J, Moon S Y, Park J P and Lee SY . : In Silico prediction of the importance of Enter-Doudoroff pathway in poly(3-hydroxybutyrate) production, KMB meeting,Gyunbook univ., October,26(2002)

27. AJ Song, SJ Park, JP Park, SY Lee. : Newly screened Pseudomonas sp. producing polyhydroxyalkanoates consisting of SCL and MCL monomers, Annual meeting of Korean society for Biotechnology and Bioengineering Symposium, Pukyong Univ, April 11-12, Pusan

28. JP Park, SJ Lee, SY Lee. : Preliminary study of an efficient secretory system of recombinant fusion protein in Escherichia coli using the PHB depolymerase signal sequence, Annual meeting of Korean society for Biotechnology and Bioengineering Symposium, Pukyong Univ, April 11-12, Pusan

29.  J. P. Park, S. J. Lee, T. J. Park, S. Y. Lee, H. S. Lee, H. T. Jung, : Enzyme-based Biomolecular Engineering of Single-Walled Carbon Nanotubes (SWNTs) by Transglycosylation Reaction, Annual Meeting of the Korean Society for Biotechnology and Bioengineering, October 22-24, Seoul, Korea (2003) 

30. Tae Jung Park, Jong Pil Park, Seok Jae Lee, and Sang Yup Lee, : Recombinant Protein Secretion in Escherichia coli using Several Leader Peptides, Annual Meeting of the Korean Society for Biotechnology and Bioengineering (2003)

31. Seok Jae Lee, Jong Pil Park, Tae Jung Park, Kyung-Bok Lee, Insung Choi, and Sang Yup Lee, : Patterning of Proteins Fabricated by Microcontact Printing (μCP) Method for Site-Specific Immobilization and Protein-Protein Interaction Assay, Annual Meeting of the Korean Society for Biotechnology and Bioengineering (2003) 

32. Jong Pil Park, Seok Jae Lee, Tae Jung Park, and Sang Yup Lee, : Visual Detection of Specific Protein-Protein Interaction using PHB Microsphere of Substrate Binding Domain from Alcaligenes faecalis, Annual Meeting of the Korean Society for Microbiology and Biotechnology(2003)

33. Seok Jae Lee, Jong Pil Park, Tae Jung Park, and Sang Yup Lee, : Enzyme-based Biomolecular Engineering of Single-Walled Carbon Nanotubes (SWNTs) by Transglycosylation Reaction, Annual Meeting of the Korean Institute of Chemical Engineers (2003)

34. Seok Jae Lee, Tae Jung Park, Jong Pil Park and Sang Yup Lee, : Novel PHB-based Protein Microarray using Extracellular Depolymerase Substrate Binding Domain for Site-Directed Capture Ligand to Detect Protein-Protein Interaction, Annual Meeting of the Korean Institute of Chemical Engineers (2003)

35. Park, J.P., Park, T.J., Lee, S.J., and Lee, S.Y., “Polyhydroxyalkanoates(PHAs) in Nanobiotechnology”, Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, Cheongju, Korea, October 13-15 (2004)

36. Park, J.P., Lee, S.J., Park, T.J., Lee, K.B., Choi, I.S., and Lee, S.Y., "Microcontact printing of biotin for selective immobilization of streptavidin-fused proteins and SPR analysis", Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, Daegu, Korea, April 16-17(2004)

37. Lee, S.J., Park, S.J., Park, T.J., Choi, J.H., and Lee, S.Y., "Self-assembly of functional bacterial surface protein and its use in nanobiotechnology", Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, Daegu, Korea, April 16-17(2004)

38. Lee, S.J., Park, S.J., Park, T.J., and Lee, S.Y., "Bioactivation of poly(3-hydroxybutyrate) microsphere and its application in a bead-based assay", Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, Daegu, Korea, April 16-17(2004)

39. Park, T.J., Park, J.P., Lee, S.J., and Lee, S.Y., "Artificial surface display system in Escherichia coli using exosporal agent", Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, Daegu, Korea, April 16-17(2004)

40. Kang, Y.J., Park, J.P. and Lee, S.Y., "Micropattern Generation of Proteins on Gold Surface using Fusion Protein Strategy and Microcontact Printing", Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, April 15-16 (2005)

41. Park, J.P., Jung, D.H., Kang, Y.J., Ko, Y.K, Jung, H.T. and Lee, S.Y., "Controlled Networks of Single-Walled Carbon Nanotubes(SWNTs) Arrays by Functionalized Magnetic Microbeads under Ultra-Low Magnetic Field", Annual Meeting of Korean Society for Biotechnology and Bioengineering Symposium, April 15-16 (2005)

 

  2). International Conferences

1. Park JP and Yun JW : Continuous production of inulo-oligosaccharides from chicory juice by immobilized endoinulinase. 9th European Congress on Biotechnology (ECB9), Brussels, Belgium (1999.7)

2. Bae JT, J Sinha, Park JP, and Yun JW : Optimization of submerged culture conditions for exo-biopolymer production by Paecilomyces japonica. Asian Mycological Congress 2000, Hong Kong (2000.7)

3. Cho YJ, JP Park, JT Bae, JW Yun: Production of inulooligosaccharide from chicory extract by dual endoinulinase system of Pseudomonas spp. and Xanthomonas spp. Biotechnology 2000, The World Congress on Biotechnology, 3-8 September, Berlin, Germany (2000)

4. JP Park, HJ Hwang, JT Bae, J Sinha and JW Yun: Production of biopolymers with biological activities by submerged culture of mushrooms. 11th World Congress of Food Science and Technology. April 22-27, 2001, Seoul

5. YJ Cho, YM Kim, JP Park, J Sinha and JW Yun: Production of high-content oligosaccharides from inulin by two types of endoinulinase preparations from Xanthomonas sp. and Pseudomonas sp. 11th World Congress of Food Science and Technology. April 22-27, 2001, Seoul

6. HJ Hwang, SW Kim, JP Park, CH Song, JW Yun: Effect of substrate concentration on broth rheology and fungal morphology during exo-biopolymer production by P. japonica in a batch bioreactor. 6th World Congress of Chemical Engineering. Sep 23-27, 2001, Melbourne

7. SW Kim, HJ Hwang, JP Park, JW Yun: Optimization of submerged culture conditions for the mycelial growth and exo-biopolymer production by C. militaris. 6th World Congress of Chemical Engineering. Sep 23-27, 2001, Melbourne

8. Seung Hwan Lee, Jong Pil Park, Si Jae Park, Sang Yup Lee : Biosynthesis of medium-chain-length polyhydroxyalkanoates in recombinant E. coli by engineering beta-oxidation pathway. 9th International Symposium on the genetics of industrial microorganism. July1-5, 2002, Gyeongju, Korea

9. Jong Pil Park, Si Jae Park, San Yup Lee : Production of the medium-chain-length polyhydrxoyalkanoates in methabolically engineered E. coli strains. 9th International Symposium on the genetics of industrial microorganism. July1-5, 2002, Gyeongju, Korea

10. Si Jae Park, Jong Pil Park, Sang Yup Lee : Biosynthesis of poly(3-hydroxybutyrate-co-hydroxyalkanoate) in metabolically engineered E. coli strains. 9th International Symposium on the genetics of industrial microorganism. July1-5, 2002, Gyeongju, Korea

11. JP Park, SJ Park, SY Lee: Biosynthesis and characterization of polyhydroxyalkanoates in newly screened Pseudomonas sp. MBEL21. ISBP, Sep 22-26, Germany (Oral)

12. SJ Park, JP Park, SY Lee: Biosynthesis and characterization of polyhydroxyalkanostes from newly screened strain from sludge. ISBP, Sep 22-26, Germany

13. SJ Park, JP Park, SY Lee: Amplification of glycolytic pathway increases the yield of poly(3-hydroxybutyric acid ) in E. coli. ISBP, Sep 22-26, Germany

14. SJ Park, JP Park, SY Lee: Production of (R)-(-)-3-hydroxybutyric acid by metabolically engineered E.coli. ISBP, Sep 22-26, Germany

15. JH Choi, JP Park, Si Jae Park, Sang Yup Lee : Metabolic engineering of Escherichia coli for the production of polyhydroxyalkanoates consisting of short-chain-length and medium-chain-length monomers. Metabolic Engineering IV: Applied System Biology, October 6-11, 2002, Italy

16. Seung Hwan Lee, Si Jae Park, Jong Pil Park, Sang Yup Lee: Metabolic engineering of Escherichia coli for the production of medium-chain-length polyhydroxyalkanoates. Metabolic Engineering IV: Applied System Biology, October 6-11, 2002, Italy

17. Jong Pil Park, SJ Lee, TJ Park, SY Lee: Visual detection of specific protein-protein interaction using PHB microsphere of substrate binding domain from Acaligenes faecalis. 2003 Annual meeting and international symposium of the KMB, June 24-26, Muju, Korea

18. SJ Lee, JP Park, SY Lee: Selective immobilization of proteins on phb-based microarray using extracellular depolymerase substrate binding domain for site-directed capture ligand to detect protein-protein interaction. BioChE-03, July 19-23, 2003, Boulder, Colorado, USA

19. Seok Jae Lee, Jong Pil Park, Tae Jung Park, and Sang Yup Lee, : Selective Immobilization of Proteins on PHB-Based Microarray using Extracellular Depolymerase Substrate Binding Domain for Studying Protein-Protein Interaction, BioChE-03. Biochemical Engineering (XIII) Conference (2003)

20. Jong Pil Park, Seok Jae Lee, Tae Jung Park, Kyung-bok Lee, Insung S Choi, and Sang Yup Lee, : Patterning of Poly(3-hydroxybutyrate) for Site-Selective Protein Immobilization and Studying Protein-Protein Interaction, The 2nd KAIST International Symposium on Frontier Issues in NBI Technologies (2003)

21. Seok Jae Lee, Jong Pil Park, Tae Jung Park, Kyung-bok Lee, Insung S Choi, and Sang Yup Lee, "Patterning of Proteins by Microcontact Printing", The 2nd KAIST International Symposium on Frontier Issues in NBI Technologies (2003)

22. Jong Pil Park, Seok Jae Lee, Tae Jung Park, and Sang Yup Lee, "The Structural Basis for Catalysis and Specificity of the Substrate Binding Domain of PHB Depolymerase from Bacteria" Enzyme Engineering XVII (2003)

23. Jong Pil Park, Seok Jae Lee, Tae Jung Park, and Sang Yup Lee, "Bead-Based System for Studying Protein-Protein Interactions using PHB Microsphere with Substrate Binding Domain", Enzyme Engineering XVII ( 2003)

24. Jong Pil Park, Seok Jae Lee, Tae Jung Park, and Sang Yup Lee, "Microbial Polyamide Production by Recombinant Escherichia coli", Enzyme Engineering XVII, (2003)

25. Lee, S. J., Park, J. P., Park, T. J., Lee, S. Y., "Peptide arrays Improvedby the Protein layer for Protein Kinase Assay", 227th ACS National Meeting, Anaheim, CA, March 28-April 1 (2004)

26. Park, J. P., Park, T. J., Lee, S. J., Choi, J. H., and Lee, S. Y., "Self-assembly of functional bacterial surface protein around carbon nanotube and its use in nanostructure fabrication", 227th ACS National Meeting, Anaheim, CA, March 28-April 1 (2004)

27. Park, T. J., Park, J. P., Lee, S. J., Lee, K.-B., Choi, I. S., and Lee, S. Y., "Patterning of polyhydroxyalkanoates for selective protein immobilization and studying protein-protein interaction", 227th ACS National Meeting, Anaheim, CA, March 28-April 1 (2004)

28. S.J. Lee, J.P. Park, T.J. Park, K.-B. Lee, I.S. Choi, S.Y Lee. Microcontact printing of biotin for selective immobilization of streptavidin-fused proteins and its application for biosensor using SPR analysis. Biosensor 2004, Spain (2004)

29. J.P. Park, S.J. Lee, T.J. Park, S.M. Yoo, D. Lee, S.Y. Lee. Systematic detection of pathogenic bacteria using carbohydrate-encapsulated quantum dot. Biosensor 2004, Spain (2004)

30. Jae Shin Lee, Do Hyun Kim, Seok Jae Lee, Jong Pil Park, Tae Jung Park, Sang Yup Lee, Dae-Hwan Jung, Hee-Tae Jung, Jin Hee Kim, and Seong Ku Kwon. Eltrical detection of kinase assay using multi walled-carbon nanotube(mwcnt) nanoelectrode. microTAS 2004 Malmo Sweden. 26-30 Sep.

31. Jong Pil Park, Seok Jae Lee, Kwang Suk Yang, Yong Beom Shin, Bong Hyun Chung, Do Hyun Kim, and Sang Yup Lee. Fabrication of Gold Binding Protein Fusion Protein Arrays for Surface Plasmon Resonance Imaging Studies of Protein-Protein and DNA Hybridization Assays. ISNM, Daejeon, KAIST (2004.11.3)

32. Park, J.P., Lee, S.J., Choi, J.H., Lee, S.Y., "Self-Assembly of Functional Bacterial Surface Protein around Carbon Nanotubes and Its Application", ISNM, Daejeon, Korea (2004)

33. Park, J.P., Lee, S.J., Lee, K.B., Choi, I.S., Kim, M.G., Chung, B.H., Lee, S.Y., "Microcontact Printing and SPR Analysis of Biotin for Selective Immobilization of Streptavidin-fused Proteins". ISNM, Daejeon, Korea (2004)

34. Park, J.P., S.J., Lee., Hong, H.J., Lee, S.Y., “Fabrication of Polyhydroxyalkanoate (PHA) Chip for Studying Protein-Protein Interactions”, Yonsei University, December 3, Korea (2004)

Dong Yup Lee

Details

 1. Education

2. Research Experiences

3. Awards

4. Software

5. Publications

6. Presentations

7. Projects


Ha Na Park

Details

 Education

Seung Hyun Lee

Joong Hoon Lee

Seong Hwan Lee

Details

 1. Research Interest

2. Education

3. Sissertation title

 

4. Publications

1. Lee, S.H., Oh, D.H., Ahn, W.S., Lee, Y., Choi, J., and Lee, S.Y. , “Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by high cell density cultivation of Aeromonas hydrophila”, Biotechnol. Bioeng. 67:240-244(2000)

2.  Lee, S.Y. , Choi, J., and Lee, S.H. “Production of polyhydroxyalkanoates by fermentation of bacteria”Macromol. Symp. 159:259-266(2000)

3.  Lee, S.Y. , Wong, H.H., Choi, J., Lee, S.H., Lee, S.C., and Han, C.S., “Production of medium-chain-length  polyhydroxyalkanoates by high cell density cultivation of  Peudomonas putida under phosphorus limitation”, Biotechnol. Bioeng., 68:466-470(2000)

4. Park, S.H., Lee, S.H., and Lee, S.Y., "Preparation of optically active beta-amino acids from microbial polyester polyhydroxyalkanoates", J. Chem. Reseach (S), 498-499(2001)

5. Lee, S.Y., Hong, S.H., Lee, S.H., Park, S.J. "Fermentative Production of Chemicals That Can Be Used for Polymer Synthesis", Macromolecular Bioscience, 4 : 157-164 (2004).

6. Lee, S. H., Choi, J., Park, S. J., Lee, S.Y., Park, B. C. " Display of bacterial lipase on the Escherichia coli cell surface by using FadL as an anchoring motif and its use in enantioselective biocatalysis", Appl. Environ. Microbiol. 70(9) : 5074-5080 (2004).

7. Lee, S. H., Choi, J.H., Park, S.H., Choi, J.-I., and Lee, S.Y., "Enantioselective resolution of racemic compounds by cell surface displayed lipase", Enzyme Microbial Technol., 35 : 429-436 (2004).

8. Lee, S.H., Choi, J.-I., Han, M.-J., Choi, J.H., and Lee, S.Y. "Display of lipase on the cell surface of Escherichia coli using OprF as an anchor and its applications to enantioselective resolution in organic solvent", Biotechnol. Bioeng. in press(2004).

1. Lee, Y., Lee, S.H., Lee, S.Y.  “Fed-batch culture of Aeromonass hydrophila for the production of poly(3-hydroxybutyrate-co-hydroxyhexanoate) using two carbon sources”, Biotechnol.Bioproc. Eng. 4:195-198(1999)

2.  Choi, J.-I., Lee, S.H., and Lee, S.Y., "Isolation and characteristics of polyhydroxyalkanoates producing Pseudomonas sp. MBEL21", Kor. J. Microbiol. Biotechnol. 32(2) : 123-127 (2004).